Research progress in toxicological mechanism and prevention strategy of deoxynivalenol

DENG Yiqun; LIN Ruqin; WU Siting; YU Danni; LIU Si

doi:10.7671/j.issn.1001-411X.202208017

Journal of South China Agricultural University > 2022 > 43(6): 87-96. > DOI: 10.7671/j.issn.1001-411X.202208017

DENG Yiqun, LIN Ruqin, WU Siting, et al. Research progress in toxicological mechanism and prevention strategy of deoxynivalenol[J]. Journal of South China Agricultural University, 2022, 43(6): 87-96. DOI: 10.7671/j.issn.1001-411X.202208017

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Research progress in toxicological mechanism and prevention strategy of deoxynivalenol

College of Life Sciences, South China Agricultural University/Guangdong Provincial Key Laboratory of Protein Function and Regulation in Agricultural Organisms/Guangdong Laboratory for Lingnan Modern Agriculture/ Key Laboratory of Zoonosis of the Ministry of Agriculture and Rural Affairs, Guangzhou 510642, China

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Received Date: August 09, 2022
Available Online: May 17, 2023

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Abstract

Abstract

Deoxynivalenol (DON) is one of the most common and serious polluted mycotoxins that contaminate grains, feed ingredients and feed. The acute or chronic poisoning symptoms of feed-borne exposure to DON in animals are vomiting, diarrhea, feed refusal, weight loss and even death, which seriously threatens the healthy breeding of animal. The toxicity mechanism and metabolic transformation of DON are the research hotspots in the fields of agriculture and food. This article reviews the latest domestic and international research progress in the cytotoxicological mechanism, biological prevention methods and detoxification microorganism screening of DON. It is expected to provide references for prevention and control of the harm of DON to animal.
- Deoxynivalenol,
- Mycotoxin,
- Toxicology,
- Biological control,
- Detoxification microorganism

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References (93)

References

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Research progress in toxicological mechanism and prevention strategy of deoxynivalenol

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