Abstract: In order to determinate mating ability of three-line hybrid sows, we compared the growth and development performances of five kinds of hybrid sows, including W211, W212, W362, W351 and W352, and mated the S121 boar with five hybrid sows respectively to produce commercial pigs in Huanggong pig farm of Huanong Wens. The growth performance, carcass performance, body comformation and reproductive performance of different hybrid sows were compared. The results showed that the body comformation of different hybrid sows had certain differences. The body length of W211 pig was short and its teat number was less; The effective teat number of W212 pig was more and its body length was medium; The effective teat number of W362 pig was less and its body length was long; The effective teat number of W351 pig was less and its body length was long; The body length of W352 pig was the longest and its effective teat number was more. The farrowing performance and farrowing rate of W352 sows were better than those of W211 sows. The total number born, number born alive, number born robust of W352 first-born sows was 0.7, 0.6, 0.5 higher than that of W211 respectively. The total number born, number born alive, number born robust of W352 multiparous sows was 0.7, 0.9, 0.8 higher than that of W211. W352 sow had a rapid growth rate and a slightly thicker back fat. There was a certain heterosis in different hybrid sows, but the heterosis of W352 sow in litter size was more obvious (more than 5%). W352 line has the advantages of high body length and reproductive performance. Using three-line hybrid sows because of its heterosis and high yield, the average added profit per head of slaughter pig reachs more than 13.9 yuan.