鸡传染性法氏囊病BK912变异株疫苗安全及效力试验
SEFETY AND BFFICACY TESTS OF INFECTIOUS BURSAL DISEASE VARIANT STRAIN VACCINE BK912
-
摘要: 使用3批IBD-BK912冻干疫苗对20日龄在隔离器中饲养的SPF鸡经2次点眼、口服各2000TCID50,干二免后14天用100BID501084A法氏囊囊毒攻毒,对照组100%发病,免疫的3个组100%保护,通过对囊指数的测定,疫苗安全,对囊无损伤。Abstract: There groups of 20-day-old SPF chicks raised in isolators were vaccinated by ocu-lar instillation and oral administration with three batches of IBD BK912 lyophilized vaccinerespectively.Booster was carried out 2 weeks later with the same method.Two weeks afterthe booster,one control group and three vaccinated groups were challenged with 100BID501084A strain.Results showed 100%morbidity for the control group and 100%protectionfor the vaccinated groups.Determination of bursa index as well as protection test reveal thatthe vaccine was safe and did no harm to the bursa.
-
Keywords:
- IBD variant strain /
- Vaccine /
- Immunity
-
计量
- 文章访问数: 1077
- HTML全文浏览量: 4
- PDF下载量: 1096