Abstract: Observations on the evoked potential of the cerebral cortex ( CEP ) and the spinal cord surface ( SSP ) induced by electro-rtimulation of the tibial nerve under the influence of electro-acupuncture in 15 goats are reported in the present paper. Experiments results revealed that the inhibitory effect of the electro-acupuncture appeared both in the CEP and the SSP. It was also noted that while the former was completely inhibited the latter showed only slight inhibition. It indicates that the CEP as compare with the SSP is more facile to be inhibited under the influence of the electro-acupuncture.